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Improved dissolution and anti-inflammatory effect of ibuprofen by solid dispersion

Liyuan Chen, Qifeng Dang, Chengsheng Liu, Jun Chen, Lei Song, Xiguang Chen

Frontiers of Medicine 2012, Volume 6, Issue 2,   Pages 195-203 doi: 10.1007/s11684-012-0189-3

Abstract:

The purpose of this study was to improve the dissolution rate and anti-inflammatory effect of ibuprofenThe anti-inflammatory effect of SDBT was evaluated using the mouse ear edema test with xylene.SDBT displayed more significant anti-inflammatory effects than CT.The dissolution rate and anti-inflammatory effect of ibuprofen were significantly enhanced by the ibuprofen-urea

Keywords: ibuprofen     solid dispersion     physical mixture     dissolution     anti-inflammatory effect    

Genomic Analysis of Lactobacillus fermentum Strains and the Key Genes Related to Their Intestinal Anti-inflammatory Article

Yan Zhao, Chengcheng Zhang, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai

Engineering 2022, Volume 17, Issue 10,   Pages 170-182 doi: 10.1016/j.eng.2020.09.016

Abstract:

•Some specific genes may account for the anti-inflammatory and immunoregulation of branches of the phylogenetic tree and strain type L. fermentum CECT5716 were selected and their anti-inflammatoryThe anti-inflammatory mechanisms of L. fermentum FXJCJ61 and CECT5716 were related to the inhibitionComparative genomic analysis of these strains identified candidate genes that may contribute to the anti-inflammatory

Keywords: Lactobacillus fermentum     Ulcerative colitis     Anti-inflammation     Phylogenetic analysis     Comparative    

Modulatory effect on dyslipidemia and anti-atherosclerotic function of in newly diagnosed type 2 diabetes

SUN Mingxiao, WANG Yao, CHI Jiamin

Frontiers of Medicine 2008, Volume 2, Issue 2,   Pages 174-177 doi: 10.1007/s11684-008-0032-z

Abstract: The modulatory effect of on dyslipidemia and the preventive effect on atherosclerosis in newly diagnosed

Anti-hyperglycemic effect of the polysaccharide fraction isolated from mactra veneriformis

Lingchong WANG, Hao WU, Nian CHANG, Kun ZHANG

Frontiers of Chemical Science and Engineering 2011, Volume 5, Issue 2,   Pages 238-244 doi: 10.1007/s11705-010-0002-2

Abstract: The anti-hyperglycemia effects of the crude polysaccharide part were preliminarily investigated usingpolysaccharide fraction exhibited proper glycemia inhibition activity, and 300 mg/kg-weight dose has the optimal effectcrude polysaccharide fraction can be explored as a novel health product that possesses potential as an anti-hyperglycemic

Keywords: anti-hyperglycemia     Mactra veneriformis     polysaccharide     monosaccharide composition     oral    

Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 139-145 doi: 10.1007/s11684-015-0377-z

Abstract: view is supported by a large body of literature, it has been challenged by growing evidence that pro-inflammatoryarticle, interleukin 15 (IL-15) is used as a new example to explain the beneficial effects of the pro-inflammatoryIn the anti-obesity effects of IL-15, T cells and NK cells are not required, but leptin receptor is requiredIn summary, evidence from human and rodents supports that the pro-inflammatory cytokine IL-15 may enhance

Keywords: inflammation     obesity     cytokine     energy expenditure     insulin resistance    

CD47 blockade improves the therapeutic effect of osimertinib in non-small cell lung cancer

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 105-118 doi: 10.1007/s11684-022-0934-1

Abstract: In this study, OSI induced higher CD47 expression, an important anti-phagocytic immune checkpoint, viaThe combination treatment of OSI and the anti-CD47 antibody exhibited dramatically increasing phagocytosisin HCC827 and NCI-H1975 cells, which highly relied on the antibody-dependent cellular phagocytosis effectMeanwhile, combining the anti-CD47 antibody significantly augmented the anticancer effect of OSI in HCC827findings suggest the multidimensional regulation by OSI and encourage the further exploration of combining anti-CD47

Keywords: osimertinib     anti-CD47 antibody     combination strategy     ADCP     EGFR    

Effect of levonorgestrel intrauterine system on IGF-1 and the dependablity study of prevention pelvicinflammatory disease

Wu Xiaojie,Liu Xia,Tao Yueping,Wang Jie

Strategic Study of CAE 2015, Volume 17, Issue 6,   Pages 4-7

Abstract:

Objective: To study the effect of levonorgestrel Intrauterine System on insulin-like growth factor-l(IGF-1) and the result of levonorgestrel Intrauterine System Prevention pelvic inflammatory disease.Patients were followed up for 2Syears to analyse the effluence of pelvic inflammatory disease.Followed up for 2 years, 14 cases has pelvic inflammatory disease in study group,39 cases has pelvicinflammatory disease in control group,there was a significant differences.

Keywords: levonorgestrel     Intrauterine system insulin-like growth factor-1     pelvic inflammatory disease    

Effect of IL-10 on formation of foam cell induced by ox-LDL

WANG Fei, DAI Yalei, XU Ting, XU Bo, WANG Kaifeng

Frontiers of Medicine 2008, Volume 2, Issue 3,   Pages 298-302 doi: 10.1007/s11684-008-0057-3

Abstract: IL-10, an anti-inflammatory cytokine, can inhibit the effect of ox-LDL and LPS.These results indicate that inflammatory effects in blood vessels can speed up foam cell formation.The inhibitive effect of IL-10 is an important factor for delaying atherosclerosis processes.

Keywords: inflammatory     presence     interleukin-10     dose-dependent     ox-LDL    

Bioactive hyaluronic acid fragments inhibit lipopolysaccharide-induced inflammatory responses via the

Na You, Sasa Chu, Binggang Cai, Youfang Gao, Mizhou Hui, Jin Zhu, Maorong Wang

Frontiers of Medicine 2021, Volume 15, Issue 2,   Pages 292-301 doi: 10.1007/s11684-020-0806-5

Abstract: However, the role of LMW-HA in inflammatory response is controversial.In this study, we aimed to investigate the effect of bioactive hyaluronan (B-HA) on lipopolysaccharide(LPS)-induced inflammatory responses in human macrophages and mice.that B-HA inhibited the expression of TNF-α, IL-6, IL-1, and IFN-β, and enhanced the expression of the anti-inflammatoryB-HA could be a potential anti-inflammatory drug in the treatment of inflammatory disease.

Keywords: bioactive hyaluronan     lipopolysaccharide     inflammatory cytokines     TLR4     human macrophages    

QUANTITATIVE STUDY ON ANTI-PEST ACTIVITY OF NATURAL PRODUCTS BASED ON VISUALIZATION FRAMEWORK OF KNOWLEDGE

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 2,   Pages 306-332 doi: 10.15302/J-FASE-2023488

Abstract:

● Using visual analysis to predict the trend of natural product pest resistance.

Keywords: anti-pest activity     crop protection     insect pest     natural product     visual analysis    

Dihydroartemisinin increased the abundance of by YAP1 depression that sensitizes hepatocellular carcinoma to anti-PD

Frontiers of Medicine 2023, Volume 17, Issue 4,   Pages 729-746 doi: 10.1007/s11684-022-0978-2

Abstract: The effect of anti-programmed cell death 1 (anti-PD-1) immunotherapy is limited in patients with hepatocellularThe response to anti-PD-1 treatment is associated with A. muciniphila abundance in many tumorsHere, anti-PD-1 treatment decreased A. muciniphila abundance in the colon, but increased YAP1Yap1 knockout enhanced anti-PD-1 efficacy.Our findings suggested that the combination anti-PD-1 with DHA is an effective strategy for liver tumor

Keywords: hepatocellular carcinoma     YAP1     Akkermansia muciniphila     anti-PD-1     dihydroartemisinin     bile acid    

Curcumin based combination therapy for anti-breast cancer: from

Sunhui Chen,Qiuling Liang,Shuping Xie,Ergang Liu,Zhili Yu,Lu Sun,Meong Cheol Shin,Seung Jin Lee,Huining He,Victor C. Yang

Frontiers of Chemical Science and Engineering 2016, Volume 10, Issue 3,   Pages 383-388 doi: 10.1007/s11705-016-1574-2

Abstract: mechanisms as a depressor of chemo-resistance, can significantly facilitate its anti-cancer functionsTo explore this possibility, four anti-cancer chemotherapeutic agents that all possess a certain degreeeffect both and .that sunitinib combined with curcumin at the molar ratio of 0.46 yielded the most potent synergistic effectTo further enhance the anti-cancer effect, bovine serum albumin (BSA) nanoparticles were utilized as

Keywords: curcumin     sunitinib     synergistic effect     bovine serum albumin (BSA)     nano-carriers    

A modular cable-driven humanoid arm with anti-parallelogram mechanisms and Bowden cables

Frontiers of Mechanical Engineering 2023, Volume 18, Issue 1, doi: 10.1007/s11465-022-0722-2

Abstract: This paper proposes a novel modular cable-driven humanoid arm with anti-parallelogram mechanisms (APMs

Keywords: modular robotic arm     anti-parallelogram mechanism     Bowden cable     humanoid arm     lightweight joint design    

Anti-biofouling strategies for implantable biosensors of continuous glucose monitoring systems

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 12,   Pages 1866-1878 doi: 10.1007/s11705-023-2340-x

Abstract: review, research efforts over the past few years to mitigate the immune responses by enhancing the anti-biofoulinglayers on the biosensor surface, such as drug-releasing membranes, hydrogels, hydrophilic membranes, anti-biofoulinginformation, which is likely to aid in the research and development of novel CGM systems with profound anti-biofouling

Keywords: implantable glucose biosensor     anti-biofouling     continuous glucose monitoring     immune responses    

Lignin-derived dual-function red light carbon dots for hypochlorite detection and anti-counterfeiting

Frontiers of Chemical Science and Engineering 2023, Volume 17, Issue 7,   Pages 966-975 doi: 10.1007/s11705-022-2244-1

Abstract: Compared with green and blue fluorescent materials, red SPN-CDs have desirable anti-interference properties

Keywords: alkali lignin     red light carbon dots     hypochlorite     encryption and anti-counterfeiting    

Title Author Date Type Operation

Improved dissolution and anti-inflammatory effect of ibuprofen by solid dispersion

Liyuan Chen, Qifeng Dang, Chengsheng Liu, Jun Chen, Lei Song, Xiguang Chen

Journal Article

Genomic Analysis of Lactobacillus fermentum Strains and the Key Genes Related to Their Intestinal Anti-inflammatory

Yan Zhao, Chengcheng Zhang, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai

Journal Article

Modulatory effect on dyslipidemia and anti-atherosclerotic function of in newly diagnosed type 2 diabetes

SUN Mingxiao, WANG Yao, CHI Jiamin

Journal Article

Anti-hyperglycemic effect of the polysaccharide fraction isolated from mactra veneriformis

Lingchong WANG, Hao WU, Nian CHANG, Kun ZHANG

Journal Article

Beneficial metabolic activities of inflammatory cytokine interleukin 15 in obesity and type 2 diabetes

Jianping Ye

Journal Article

CD47 blockade improves the therapeutic effect of osimertinib in non-small cell lung cancer

Journal Article

Effect of levonorgestrel intrauterine system on IGF-1 and the dependablity study of prevention pelvicinflammatory disease

Wu Xiaojie,Liu Xia,Tao Yueping,Wang Jie

Journal Article

Effect of IL-10 on formation of foam cell induced by ox-LDL

WANG Fei, DAI Yalei, XU Ting, XU Bo, WANG Kaifeng

Journal Article

Bioactive hyaluronic acid fragments inhibit lipopolysaccharide-induced inflammatory responses via the

Na You, Sasa Chu, Binggang Cai, Youfang Gao, Mizhou Hui, Jin Zhu, Maorong Wang

Journal Article

QUANTITATIVE STUDY ON ANTI-PEST ACTIVITY OF NATURAL PRODUCTS BASED ON VISUALIZATION FRAMEWORK OF KNOWLEDGE

Journal Article

Dihydroartemisinin increased the abundance of by YAP1 depression that sensitizes hepatocellular carcinoma to anti-PD

Journal Article

Curcumin based combination therapy for anti-breast cancer: from

Sunhui Chen,Qiuling Liang,Shuping Xie,Ergang Liu,Zhili Yu,Lu Sun,Meong Cheol Shin,Seung Jin Lee,Huining He,Victor C. Yang

Journal Article

A modular cable-driven humanoid arm with anti-parallelogram mechanisms and Bowden cables

Journal Article

Anti-biofouling strategies for implantable biosensors of continuous glucose monitoring systems

Journal Article

Lignin-derived dual-function red light carbon dots for hypochlorite detection and anti-counterfeiting

Journal Article